阳性气道压力耐受性和粘附性之间的关系:定义一个新的度量
Sruti Tekumalla1, Andrea Plawecki2,3, Thomas Kaffenberger2,3
1Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.
概括
阳性气道压力 (PAP) 治疗耐受性显著影响患者的坚持. 更高的耐受性得分与更好的坚持相关,这表明耐受性是成功治疗PAP治疗结果的关键因素.
科学领域:
- 睡眠医学 睡眠医学
- 呼吸系统疗法 呼吸系统疗法
背景情况:
- 阳性气道压力 (PAP) 治疗的坚持率低于最佳,从30%到60%不等.
- 尽管坚持PAP治疗,但患者对PAP治疗的不满可能会发生.
- 识别影响PAP耐受性的因素对于改善坚持至关重要.
研究的目的:
- 调查阻塞性睡眠呼吸暂停患者的阳性气道压力 (PAP) 耐受性和坚持性之间的关系.
- 为了确定预测PAP耐受性的因素.
- 探索PAP耐受性的潜力,作为预测粘附性的指标.
主要方法:
- 对105名阻塞性睡眠呼吸暂停患者进行了10个问题的PAP耐受性调查,开始PAP治疗.
- 该调查使用视觉模拟尺度评估了心理社会感知,实际问题和副作用.
- 统计分析,包括t测试,多变量回归和递归分区,用于探索耐受性,坚持性和患者变量之间的关系.
主要成果:
- 在坚持治疗的患者中观察到更高的PAP耐受性得分 (P = .033).
- 耐受性得分与入睡能力 (P = .013) 和整夜睡眠能力 (P = .020) 有积极的关联.
- 抑郁症正面预测了耐受性 (P = .006),而失眠药物使用则负面预测了耐受性 (P = .010).
结论:
- 耐受性是影响治疗坚持的重要因素.
- PAP耐受性可以根据坚持数据统计定义和分类.
- PAP耐受性显示为一个有前途的预测工具,用于评估未来的坚持.
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