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在严重疾病后的幸存者中,随着时间的推移,抑郁症状:系统性审查和元分析
Zhongyan Du1, Xiaojun Liu1, Yuanyuan Li2
1School of Nursing and Rehabilitation, Shandong University, Jinan 250000, China.
General hospital psychiatry
|February 2, 2024
概括
抑郁症状影响了大约五分之一的严重疾病的成年幸存者,在重症监护室出院后持续很长时间. 这凸显了对这些患者持续提供心理健康支持和康复服务的重大需求.
科学领域:
- 关键护理医学 关键护理医学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 严重疾病的幸存者经常经历抑郁症状,影响恢复和日常功能.
- 这些症状在幸存者中的确切患病率尚不清楚,尽管有报道的变化.
研究的目的:
- 系统地确定严重疾病的成年幸存者的抑郁症状的总体患病率.
- 探索抑郁症症状流行,重症监护室 (ICU) 退院后的时间稳定性和潜在缓解因素.
主要方法:
- 在主要数据库 (PubMed,Embase,CINAHL,PsycINFO) 进行了全面的系统文献搜索,截至2023年8月.
- 涉及24,849名成年重症幸存者的52项观察性研究被纳入了使用随机效应模型的元分析.
- 通过Joanna Briggs Institute的工具和GRADE方法来评估研究质量,使用子组分析和元回归来调查异质性.
主要成果:
- 在重症病幸存者中,抑郁症状的综合患病率估计为21.1% (95% CI,18.3-24.1%).
- 随着时间的推移,患病率保持相对稳定,点位估计在ICU出院后的不同间隔 (3个月至12个月以上) 从18.5%到22.6%不等.
- 在出院后的不同时间点中,没有观察到患病率的显著变化.
结论:
- 抑郁症状是大约五分之一的成年严重疾病幸存者的重要关注点,在重症监护室 (ICU) 退院后持续一年或更长时间.
- 这些发现强调了对康复服务需求的预期增长以及风险分层的必要性,以实现最佳的临床决策.
- 预防和管理抑郁症状的积极措施在整个ICU患者护理连续过程中至关重要,从ICU停留到医院后康复.
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