高质量或低质量的碳水化合物与抑郁症状和基于XGboost算法的社会经济饮食因素模型之间的关联:来自NHANES 2007-2018年
Xiangji Dang1, Ruifeng Yang2, Qi Jing2
1Department of Pharmaceutical, Lanzhou University Second Hospital, Cui Ying Men No.80, Lanzhou 730030, Gansu Province, PR China.
Journal of affective disorders
|February 2, 2024
概括
饮食中的碳水化合物质量会影响抑郁症状. 高质量的碳水化合物与较少的症状有关,而低质量的碳水化合物与更多的症状相关. 机器学习模型可以根据饮食来预测抑郁症的严重程度.
科学领域:
- 公共心理健康 公共心理健康
- 营养科学 营养科学
- 计算精神病学是一种计算精神病学.
背景情况:
- 抑郁症状是一个重大的公共卫生问题.
- 饮食摄入量和抑郁症之间的联系是公认的,但碳水化合物质量的作用尚不清楚.
- 这项研究调查了饮食碳水化合物质量与抑郁症状之间的关联.
研究的目的:
- 检查高质量和低质量的碳水化合物与抑郁症状之间的关系.
- 根据饮食和社会经济因素开发一种机器学习模型来预测抑郁症状.
主要方法:
- 利用了4982名参与国家健康和营养检查调查 (NHANES) 的数据.
- 通过24小时饮食回忆和使用患者健康问卷-9 (PHQ9) 的抑郁症状评估碳水化合物摄入量.
- 采用差异通胀因子 (VIF) 和缓解-F用于特征选择和XGBoost用于模型开发.
主要成果:
- 多变量回归显示,高质量的碳水化合物与抑郁症状之间存在负相关性 (p=0.002).
- 在低质量的碳水化合物和抑郁症状之间发现了积极的关联 (p=0.001).
- 开发了一个XGBoost模型来评估抑郁症状严重程度,并提供了一个在线工具.
结论:
- 饮食中的碳水化合物质量与抑郁症状有显著的关联.
- 整合饮食和社会经济数据的机器学习模型显示出预测抑郁症严重程度的前景.
- 预测模型与外部数据的进一步验证是有必要的.
相关概念视频
Depressive Disorders: Etiology
102
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
102
Overview of Carbohydrate Metabolism
1.0K
Carbohydrate metabolism is a fundamental biochemical process that ensures a constant supply of energy to living cells. The most important carbohydrate is glucose, which can be broken down via glycolysis to enter into the Krebs cycle and eventually lead to the production of ATP through oxidative phosphorylation.
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
1.0K
Human Genetics
570
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
The complex relationship between genetics and psychology is observable through common biological components such...
570
Carbohydrates: Dietary Sources and Requirements
476
Carbohydrates are predominantly obtained from plant sources. With the exception of lactose found in milk and insignificant glycogen amounts in meat, most consumed carbohydrates have plant origins. Monosaccharides and disaccharides, or sugars, can be sourced from fruits, honey, milk, sugar cane, and sugar beets. Grains and vegetables are rich in the polysaccharide starch. Two types of polysaccharides provide fiber: cellulose, which is abundant in many vegetables, forms undigestible roughage or...
476
Depressive Disorders: MDD and Dysthymia
136
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
136
Depression: Overview
244
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
244


