在COVID-19住院患者中,医院结果中的性别差异
Sandeep Appunni1, Muni Rubens, Venkataraghavan Ramamoorthy2
1From the Government Medical College, Kozhikode, Kerala, India.
Southern medical journal
|February 2, 2024
概括
患有COVID-19 (冠状病毒疾病2019) 的男性住院患者的死亡率更高,住院时间更长,重症监护室入院率更高. 男性性别是严重的COVID-19结果的重要危险因素.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 流行病学研究对COVID-19 (冠状病毒疾病2019) 流行率和结果的基于性别的差异提出了相互矛盾的数据.
- 之前的研究尚未确定男性是否与女性相比不成比例地受到COVID-19的影响.
研究的目的:
- 为了调查COVID-19住院率的基于性别的差异.
- 通过使用大型行政数据库,分析男性和女性COVID-19患者在医院治疗结果的差异.
主要方法:
- 2020年加利福尼亚州住院患者数据库的回顾性分析.
- 使用ICD-10-CM代码U07.1.1.识别COVID-19住院情况
- 住院次数按性别分层,并对结果进行比较,包括死亡率,住院时间,血管压缩器使用,机械通风和ICU入院.
主要成果:
- 在95180例COVID-19住院病例中,55.1%为男性,44.9%为女性.
- 男性住院的病例中,住院死亡率 (12.4%对10.1%),住院时间长 (30.6%对25.8%),血管压缩剂使用 (2.6%对1.6%),机械通风 (11.8%对8.0%) 和重症监护室入院 (11.4%对7.8%) 的比例明显较高.
- 后勤回归证实男性性别是增加死亡率,更长的住院时间,以及使用血管压缩剂,机械通风和ICU入院的更高率的重要风险因素.
结论:
- 男性性别是与COVID-19严重程度增加相关的独立和强有力的风险因素.
- 这些发现突出了COVID-19结果中基于性别的显著差异,强调了临床管理和公共卫生策略中需要考虑性别特异性的需要.
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