在COVID-19感染或接种疫苗的患者中,多形红血的患病率增加
Wafaa Saleh1, Hamad Alharbi2, Seunghee Cha3,4
1Oral Medicine, Periodontology, Diagnosis and Oral Radiology Department, Faculty of Dentistry, Mansoura University, Mansoura, 33516, Egypt. wafaasaid@mans.edu.eg.
Scientific reports
|February 2, 2024
概括
多形红斑 (EM) 在COVID-19感染或接种疫苗后明显更常见. 这项研究量化了增加的风险,强调了对这种皮肤状况的临床意识和患者监测的需要.
科学领域:
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 多形红疹 (EM) 已被事地与COVID-19联系在一起,但关于患病率的定量数据有限.
- 现有的报告主要是案例研究,阻碍了对EM和COVID-19之间的关联的全面理解.
- 需要进行强有力的评估,以确定与COVID-19感染和接种疫苗有关的EM的实际患病率和风险.
研究的目的:
- 在有COVID-19感染史的患者中定量确定多形红血热 (EM) 的患病率.
- 评估COVID-19感染与发展EM的风险之间的关联.
- 为了评估与普通人群相比,在接种COVID-19疫苗后发展EM的风险.
主要方法:
- 使用来自佛罗里达大学健康医院的数据进行了一项回顾性,横截面的,基于医院的研究.
- 国际疾病分类,第10版 (ICD-10) 代码用于EM,COVID-19感染和COVID-19疫苗被用于识别相关患者队列.
- 进行了统计分析,包括赔率比率,以量化与COVID-19感染和接种疫苗相关的EM风险.
主要成果:
- 该研究包括43547名有COVID-19感染史的患者,其中发现了92例EM病例.
- 与没有COVID-19的患者相比,患有COVID-19感染的患者患有EM的可能性增加了6.68倍 (P<0.0001).
- 在COVID-19疫苗接种后观察到一个统计学上显著的2.7倍的EM风险增加 (P < 0.0001).
结论:
- 在COVID-19感染或接种疫苗后,EM的患病率明显高于一般人群.
- 必须使临床医生和患者意识到增加的风险和监测EMCOVID-19后感染和/或接种疫苗的重要性.
- 进一步的研究和提高临床警对于在COVID-19大流行背景下管理EM至关重要.
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