在小鼠初级视觉皮层中,视觉,听觉和运动处理的三重分离
Matthijs N Oude Lohuis1,2,3, Pietro Marchesi1,2, Umberto Olcese1,2
1Cognitive and Systems Neuroscience Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, Netherlands.
Nature neuroscience
|February 2, 2024
概括
听觉刺激在小鼠的初级视觉皮层 (V1) 中引起反应. 研究人员将这些V1活动分离为不同的听觉和运动组件,揭示了感官输入如何相互作用以支持视觉.
科学领域:
- 神经科学是一个神经科学.
- 感官处理 感官处理
- 跨模式互动的交互.
背景情况:
- 主要感官皮层,包括主要视觉皮层 (V1),对交叉模式刺激,如听觉输入,表现出反应.
- 人们争论的是,这些反应是直接的感官输入还是行为调节的次要效应,比如声音引起的身体运动.
研究的目的:
- 为了研究声音唤起活动的性质在初级视觉皮层 (V1).
- 在V1反应中区分直接听觉感官输入和行为调制.
- 了解视觉皮层内不同输入的相互作用.
主要方法:
- 醒着小鼠的电生理学记录.
- 分析V1中神经活动对听觉刺激的反应.
- V1神经活动与面部或面部运动的相关性.
- 检查层状配置文件和神经元群体分离.
主要成果:
- 声音唤起的V1活动被分离为具有明显时空特征的听觉和行为组件.
- 听觉部件在27毫秒左右启动,起源于听觉皮层,存在于表面和深层.
- 声音唤起的口面运动,从大约80-100毫秒开始,与V1活动相关,并解释了听觉频率调.
- 听觉,运动和视觉活动被分为不同的层状形状和神经元群体.
- 在同时进行视听刺激时,视觉表现与听觉和运动活动保持区别.
结论:
- 对声音的V1反应可以归因于直接的听觉输入和声音诱导的运动活动.
- 这些听觉和运动部件具有独特的时空特征和神经元基质.
- 在V1中听觉,运动和视觉处理的分离性对于理解跨模态相互作用及其在视觉感知中的作用至关重要.
更多相关视频
08:42Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
Published on: February 8, 2020
10.0K
06:05Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging
Published on: September 18, 2015
8.3K
相关概念视频
01:14Motor and Sensory Areas of the Cortex
3.9K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
3.9K
01:24Vision
53.4K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
53.4K
01:21Association Areas of the Cortex
5.3K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
5.3K