在卫生系统专业药房的自身免疫处方医生和药剂师之间,生物相似的感知
Carly Giavatto1, Jessica Mourani1, Casey Fitzpatrick1
1CPS Solutions, LLC., Dublin, OH.
Journal of managed care & specialty pharmacy
|February 3, 2024
概括
医疗系统的处方医生和药剂师对自身免疫性疾病的自用生物类似药的知识有限,犹不决. 有针对性的教育对于改善生物类似药的采用和实现成本节约至关重要.
科学领域:
- 药物经济学 药物经济学
- 免疫学 免疫学 免疫学
- 药物开发 药物开发
背景情况:
- 在2023年底之前,即将在美国推出10种针对自身免疫疾病的自给药生物仿制药.
- 潜在的替代治疗方法和节省成本.
- 关于处方者和药剂师对这些生物类似药的看法,现有的研究有限.
研究的目的:
- 评估美国自身免疫药物处方者和卫生系统专业药剂师对生物类似药物的知识和看法.
- 确定生物类似药在自身免疫性疾病管理中的使用障碍.
主要方法:
- 匿名,横截面,自我管理的在线问卷.
- 调查分发给风湿病学,皮肤病学和胃肠病学处方医生和药剂师.
- 在2023年1月至2月期间收集的数据.
主要成果:
- 关于生物类似药的患者对话的准备程度较低 (16%的处方者,13.4%的药剂师).
- 对于已在生物治疗中患者的生物类似药的处方/推犹 (13.3%的处方者,18.1%的药剂师).
- 了解可互换和替代法规中的差距 (48%的处方者,42%的药剂师).
结论:
- 医疗保健专业人员在生物类似药方面存在重大知识缺口和犹.
- 教育举措是必要的,以加强生物类似药的采用.
- 更多的采用可以导致更大的治疗负担能力和医疗保健节省.
相关概念视频
Bioequivalence: Overview
1.0K
Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...
1.0K
Biopharmaceutics and Pharmacokinetics: Overview
2.0K
Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
2.0K
Prescription, Nonprescription and Orphan Drugs
733
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
733
Pharmacovigilance
833
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
833
Drug Abuse and Addiction: Pharmacological Phenomena
476
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
476
Combined Effects of Drugs: Antagonism
8.5K
The combined effects of drugs can result in various interactions, of which an important type is antagonism. Antagonism is a mechanism where one drug inhibits or counteracts the effects of another drug. Antagonism can occur through various means, including receptor binding, allosteric modulation, functional interaction, chemical reactions, and pharmacokinetic processes.
The most common type is receptor antagonism, where one drug acts as an antagonist to block the effects of another drug by...
The most common type is receptor antagonism, where one drug acts as an antagonist to block the effects of another drug by...
8.5K


