靠近管道的封闭首先或卵细胞的检索首先对于患者的hydrosalpinx
Jie Li1,2, Sien Mo2, Zhong Lin2
1State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, 400016, China.
Archives of gynecology and obstetrics
|February 3, 2024
概括
在体外受精-胚胎转移 (IVF-ET) 之前进行输卵管绑定显著改善了水松症妇女的怀孕结果. 与其他计时策略相比,这种方法导致更高的活产率和更低的流产率.
科学领域:
- 生殖医学 生殖医学
- 妇科 妇科 妇科 妇科
- 不孕症治疗 不孕症治疗
背景情况:
- 水晶,一种在输卵管中液体积累的情况,可以对体外受精-胚胎移植 (IVF-ET) 成功率产生负面影响.
- 与IVF-ET一起管理hydrosalpinx的最佳时间仍然是改善生育结果的关键问题.
研究的目的:
- 确定水溶管管理的最有效时机,以改善IVF-ET接受试管婴儿的患者的妊娠结果.
- 为了比较两种不同的治疗序列的疗效:近端输卵管封闭,然后是受控的卵巢过度刺激 (结合-COH) 和受控的卵巢过度刺激,然后是卵细胞检索 (COH-结合).
主要方法:
- 进行了对1490名经受试管婴儿-ET治疗的水松症患者的回顾性分析.
- 患者被分为两组:组联结-COH (首先是近道管封闭) 和组联结-COH (首先是卵细胞检索).
- 包括卵巢反应,实验室参数和临床怀孕率在内的结果使用单变量和多变量逻辑回归分析进行了比较.
主要成果:
- 与COH结合组相比,结合-COH组的生物化学怀孕率 (60.83%与46.27%),临床怀孕率 (55.69%与38.5%),活产率 (47.08%与25.26%) 和累积活产率 (69.47%与47.47%) 显著更高.
- 与COH结合组相比,结合-COH组的流产率也较低 (10.47%早产,4.49%晚产).
- 后勤回归证实了这些发现,在绑定-COH策略的怀孕和活产率显著改善,特别是在老年患者中.
结论:
- 在受控的卵巢过度刺激和卵细胞提取之前,建议在接受IVF-ET的水松症患者进行近端输卵管封闭.
- 这种序列优化了怀孕和活产率,同时降低了流产风险.
- 这些好处在老年患者中最为明显,这表明时间在这个人口群体中起着关键作用.
更多相关视频
08:46Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
6.0K
08:06Author Spotlight: Evaluating the Impact of Immediate Partial Removal of Cumulus-Oocyte Complexes on Fertilization Efficiency and Embryo Quality
Published on: October 18, 2024
413
相关概念视频
01:22Oogenesis
1.5K
Oogenesis, the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is...
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is...
1.5K
01:27Ovarian Cycle
1.2K
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
1.2K