芬兰儿童发病率的变化
Matti L Sillanpää1, Peter Camfield2, Eliisa Löyttyniemi3
1Departments of Child Neurology and Family Practice, University of Turku and Turku University Hospital, Turku, Finland.
Seizure
|February 3, 2024
概括
芬兰的儿童发病率在20世纪90年代之前一直在增加,然后稳定在每10万人/年60-70左右. 最近的数据表明,这一趋势正在下降,与产前和产周因素相关的病例较少.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 在五十年内调查芬兰儿童发病率和趋势.
- 检查儿童的人口动态和相关因素.
- 验证国家人口登记册对研究的准确性和有用性.
研究的目的:
- 确定芬兰儿童的发病率和人口趋势.
- 为了确定与儿童相关的因素.
- 评估国家卫生登记册在流行病学研究中的可靠性.
主要方法:
- 在两个不同的时间段使用医疗记录和国家登记册对儿童发病率进行比较分析.
- 使用随机样本进行对照组比较.
- 评估国家医疗保健注册,大学医院和药物注册的病例识别率.
主要成果:
- 儿童发病率从1961-1964年的38/100,000上升到1991-2000年的65.9/100,000,随后从1991-1995年到1996-2000年大幅下降.
- 与1961年至1964年相比,与产前和产周因素相关的病例在1991-2000年减少了50%.
- 国家医疗保健登记处确定了94.5%的相关病例,证明了其高度可靠性.
结论:
- 芬兰儿童发病率呈现出动态模式,增加到20世纪90年代,然后稳定,最近有证据表明下降.
- 发病率与其他工业化国家相当,表明潜在的新兴下降趋势.
- 芬兰国家登记处对于开展儿童的流行病学研究具有高度可靠性.
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