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Updated: Jul 4, 2025

Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
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Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells

Published on: March 7, 2025

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转化生长因子-β1和可溶性共抑制性免疫检查点作为基底细胞癌患者免疫抑制的假定驱动因素

Mahlatse C M Kgokolo1, Nonkululeko Z Malinga1, Helen C Steel2

  • 1Department of Dermatology, School of Medicine, Faculty of Health Sciences, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South Africa.

Translational oncology
|February 3, 2024
PubMed
概括

基本细胞癌 (BCC) 患者表现出免疫抑制可溶性免疫检查点 (SICP) 的水平升高. 转化生长因子-β1 (TGF-β1) 与这些sICPs密切相关,这表明它在与BCC相关的免疫抑制中的作用.

关键词:
阿基纳1 1 阿基纳1基底细胞癌瘤是一种基本细胞癌.在CTLA-4抗原.在PD-L1中.调控性T淋巴细胞 调控性T淋巴细胞转化生长因子-β1的转化.

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