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性冲突驱动了新的游戏生殖基因的快速演变
Nicholas W VanKuren1, Jianhai Chen1, Manyuan Long1
1Department of Ecology and Evolution, The University of Chicago, United States.
Seminars in cell & developmental biology
|February 3, 2024
概括
性冲突推动了新基因的快速进化,特别是那些具有性别偏差功能的基因. 这篇评论探讨了性冲突如何塑造新的基因进化,以果中的阿波罗和阿特米斯基因作为案例研究.
科学领域:
- 进化生物学是进化的生物学.
- 遗传学 遗传学 是一个
- 分子生物学分子生物学
背景情况:
- 快速新基因进化的进化驱动因素尚未完全理解.
- 虽然自然选择解释了一些新的基因,但许多具有性别偏差功能的基因表明性别之间存在相互矛盾的压力.
- 众所周知,性冲突 (SC) 维持了基因变异,但它在新基因进化中的作用在很大程度上尚未被探索.
研究的目的:
- 探索性冲突与新基因进化之间的联系.
- 讨论SC的概念,它的签名,以及推动新基因进化的分子机制.
- 提出一种模型来理解由SC驱动的快速新基因进化.
主要方法:
- 审查有关性冲突和新基因进化现有的文献.
- 在人群中分析SC的表型和遗传特征.
- 检查SC驱动基因进化背后的分子机制.
- 在Drosophila melanogaster中研究阿波罗和阿尔特米斯基因的案例研究.
主要成果:
- 具有性别偏差功能的新基因可能由于男性和女性之间的相互矛盾的选择性压力 (性冲突) 而演变.
- 在Drosophila melanogaster中,阿波罗和阿特米斯基因显示出快速序列进化,性特异性功能在游戏生成中,以及性对抗性健身效应.
- 这些基因可能是为了减轻SC而进化,但冲突仍然没有得到解决.
结论:
- 性冲突是一个重要的,但被低估的,推动新基因的快速进化,尤其是那些参与繁殖的基因.
- "性冲突驱动"模型为解释快速新基因进化及其对长期进化过程的贡献提供了一个框架.
- 了解SC对于解释细胞生成中基因的快速演变至关重要.
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