在肠-大脑相互作用障碍的患者报告结果
Jan Tack1, Florencia Carbone2, Lin Chang3
1Translational Research in Gastrointestinal Disorders, University of Leuven, Leuven, Belgium; Department of Gastroenterology, Leuven University Hospitals, Leuven, Belgium.
Gastroenterology
|February 3, 2024
概括
患者报告的结果对于评估肠-大脑相互作用障碍的慢性胃肠道症状至关重要. 本综述详细介绍了功能性消化不良,刺激性肠综合征和慢性便秘的可用问卷.
科学领域:
- 胃肠道学和神经生物学
- 患者报告的结果措施 (PROMs)
背景情况:
- 肠-大脑相互作用的障碍与慢性胃肠道症状存在,没有客观发现.
- 症状评估对于诊断,管理和监管评估至关重要.
- 患者报告结果 (PROM) 是结构性症状评估的关键工具.
研究的目的:
- 对主要肠-大脑相互作用障碍的可用PROM进行审查.
- 总结PROM内容,验证和监管方面的考虑.
- 突出PROM开发中的未来研究需求.
主要方法:
- 对于功能性消化不良,易怒肠综合征和慢性便秘的PROMs的文献综述.
- 分析PROM内容,临床/研究验证和监管状态.
- 综合目前的证据和未来的方向.
主要成果:
- 确定并总结了关键疾病的各种PROM.
- 评估了这些PROM的验证水平和监管机构的接受.
- 突出了当前PROM公用事业和研究中的差距.
结论:
- PROMs对于评估肠-大脑相互作用障碍至关重要.
- 需要进一步的研究来完善和扩展PROM应用.
- 标准化的PROM使用可以改善临床护理和该领域的研究.
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