酸二甲交叉连接在加载黄素的纳米纤维上,以控制释放
Jiawen Li1, Yuanhao Zheng1, Peng Wang2
1College of Biosystems Engineering and Food Science, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou 310058, China.
Food research international (Ottawa, Ont.)
|February 3, 2024
概括
绿色与酸二甲 (AD) 的交叉连接增强了纳米纤维,改善了它们的机械性能,并使控制的黄素释放成为可能. 这种氧化多糖为食品相关的电材料提供了一种可持续的方法.
科学领域:
- 材料科学 材料科学 材料科学
- 生物材料工程 生物材料工程
- 食品科学 食品科学 食品科学
背景情况:
- 纳米纤维对食品应用具有前景,但需要有效的交叉连接.
- 传统的交叉连接方法可能涉及强化学品,限制其食品安全性.
- 开发绿色交联剂对于可持续生物材料开发至关重要.
研究的目的:
- 使用绿色交叉连接来制备和表征/酸二甲基 (AD) 纳米纤维.
- 评估AD度对纳米纤维特性和性能的影响.
- 评估这些纳米纤维在黄素封装和受控释放方面的潜力.
主要方法:
- 铁/酸二甲溶液的电.
- 纳米纤维的绿色交叉连接使用酸二甲基.
- 使用红外光谱和二次结构分析进行表征.
- 评估机械性能,热稳定性,疏水性和膨胀行为.
- 黄素封装和体外释放研究.
主要成果:
- 成功制备了直径从446.2到541.8nm的Tien/AD纳米纤维.
- 实现了高度的交叉连接 (高达50.72%) 并提高了热稳定性,机械强度 (例如,Z-8的弹性模量为24.92 MPa) 和疏水性.
- 证明有效的黄素封装与可控制的释放概况.
- 观察到与释放性能相关的增强氧化抵抗.
结论:
- 酸二甲基作为一个有效的绿色交叉连接剂用于Zeen纳米纤维.
- 交叉连接过程显著提高了纳米纤维的物理和化学特性.
- 这些开发的纳米纤维显示出在食品应用中对黄素等生物活性化合物的受控输送具有很好的潜力.
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