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[临床分析COVID-19在患有先前存在的间歇性肺异常的患者中]

Y J Shi¹, R X Chen¹, X N Liu²

¹Department of pulmonary and critical care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

|February 3, 2024

概括

患有间歇性肺异常 (ILA) 的患者在感染SARS-CoV-2后患COVID-19的风险更高. 超过一半的这些患者经历了严重的COVID-19,突出显示了显著的倾向性.

科学领域:

肺部病理学肺部病理学
传染性疾病传染性疾病
放射学放射学是指放射学

背景情况:

间歇性肺部异常 (ILA) 代表了一系列的肺部疾病.
由SARS-CoV-2引起的COVID-19大流行对全球健康产生了深远的影响.
了解在患有先前存在的ILA的患者中SARS-CoV-2感染的临床过程至关重要.

研究的目的:

调查感染SARS-CoV-2的间歇性肺异常 (ILA) 患者的临床特征.
为了比较那些患有COVID-19肺炎的ILA患者的结果与那些没有的患者.
评估COVID-19的ILA患者的严重程度和治疗反应.

主要方法:

在北京联合医学院医院对38名患有先前存在的ILA患者进行了回顾性分析.
在2022年12月至2023年1月期间收集的临床数据,重点关注SARS-CoV-2感染.
在COVID-19肺炎和非肺炎组之间比较临床特征,疫苗接种状态,COVID-19特征和结果.

主要成果:

34名ILA患者感染了SARS-CoV-2;12人患上了COVID-19肺炎 (6例严重,6例中度).
在感染前的肺功能测试显示大多数患者的FVC和DLCO正常至近正常.
疫苗接种情况各不相同,未接种疫苗的人患COVID-19的发病率更高.
严重的COVID-19病例用全身皮质类固醇治疗,中度病例有不同的治疗方法.

结论:

患有间歇性肺异常 (ILA) 的患者在感染SARS-CoV-2后表现出患有COVID-19的倾向.
受 SARS-CoV-2 感染的 ILA 患者中有很大一部分患有严重的 COVID-19.
对于患有COVID-19的ILA患者来说,迅速识别和管理是必不可少的.

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