与伊朗妇女的胰岛素抵抗和内皮功能障碍相关的营养模式
Farimah Dehghani1, Zahra Hajhashemy2,3, Ammar Hassanzadeh Keshteli4
1Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, P.O. Box 14155-6117, Tehran, Iran.
Scientific reports
|February 3, 2024
概括
丰富于豆类,坚果和蛋白质食物的特定营养模式与伊朗妇女改善胰岛素抵抗和内皮功能障碍标志物有关. 相反,高动物脂肪和某些维生素的模式与更高的胰岛素抵抗指标有关.
科学领域:
- 营养科学 营养科学
- 内分泌学 在内分泌学.
- 心血管健康 心血管健康
背景情况:
- 以前的研究主要研究了单个营养素与胰岛素抵抗 (IR) 和内皮功能障碍的关联.
- 有限的研究已经探索了各种营养模式 (NP) 对这些健康参数的影响.
- 了解营养模式对于全面的饮食建议至关重要.
研究的目的:
- 调查不同营养模式 (NP) 与胰岛素抵抗 (IR) 和内皮功能障碍标志物之间的关联.
- 分析这些关联在伊朗妇女队伍中.
主要方法:
- 一项涉及368名女护士的横截面研究.
- 通过106项食物频率问卷 (FFQ) 评估饮食摄入量.
- 用于识别营养模式和它们与红外线标记物 (HOMA-IR,HOMA-β,QUICKY) 和内皮功能障碍标记物 (E-selectin,sICAM-1,sVCAM-1) 的相关性.
主要成果:
- 确定了三个主要的营养模式.
- 营养模式2 (NP2),以豆类,坚果和蛋白质食品为特征,与较低的胰岛素水平,HOMA-IR和sVCAM-1显著相关.
- 营养模式3 (NP3),高和脂肪酸,胆固醇和某些维生素,与更高的HOMA-β水平有关.
结论:
- 坚持NP2,富含,,铜,维生素B6,单不和脂肪酸 (MUFA) 和胺,与改善胰岛素敏感性和减少内皮功能障碍标志物有关.
- 随着NP3,以动物脂肪和肉加维生素E为特征,与胰岛素分泌受损的指标有关.
- 饮食模式,而不仅仅是单个营养素,在代谢和血管健康方面发挥着重要作用.
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