经过非手术治疗的急性A型大动脉剖析后的死亡率高于之前报告的死亡率
Karl Teurneau-Hermansson1,2, Jacob Ede1,2, Mårten Larsson1,2
1Department of Clinical Sciences Lund, Skåne University Hospital, Lund University, Lund, Sweden.
概括
未经治疗的急性A型大动脉解剖 (ATAAD) 的死亡率高于之前报告的,在前24小时内每小时死亡率为2.6%. 这凸显了ATAAD患者迅速诊断和紧急手术干预的急需.
科学领域:
- 心血管外科心血管外科
- 胸部外科手术 胸部外科手术
- 大动脉疾病 大动脉疾病
背景情况:
- 急性甲动脉解剖A型 (ATAAD) 是一种危及生命的疾病.
- 目前关于非手术治疗 (NST) ATAAD死亡率的现有数据有限,可能过时.
- 在前24小时内接受的每小时1-2%的死亡率是基于特定的患者队列.
研究的目的:
- 对非手术治疗 (NST) ATAAD病例进行全面审查.
- 为NST ATAAD.提供当代和准确的死亡数据.
- 重新评估未经治疗的ATAAD的普遍接受的死亡率.
主要方法:
- 在瑞典南部进行了23年 (1998-2021) 的回顾性观察性研究.
- 纳入标准:被诊断为ATAAD的患者 (ICD-9/10代码).
- 数据来源于区域医疗登记册,用于诊断确认的图表和成像检查.
主要成果:
- 在2325名查患者中,发现了184名NST ATAAD患者.
- 死亡率:47.3%在24小时内,55.0%在48小时内,76.7%在14天内,83.9%在1年内.
- 在前24小时的每小时死亡率计算为2.6%.
结论:
- 这项研究显示,NST ATAAD的死亡率明显高于之前报告的.
- 这些发现强调了快速诊断和ATAAD的立即外科治疗的关键重要性.
- 及时干预对于改善急性A型大动脉解剖患者的治疗结果至关重要.
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