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Updated: Jul 4, 2025

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
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扩大空间蛋白质组学的覆盖范围:一种机器学习方法

Huangqingbo Sun1, Jiayi Li1, Robert F Murphy1

  • 1Computational Biology Department, Carnegie Mellon University, Pittsburgh, PA 15213, United States.

Bioinformatics (Oxford, England)
|February 4, 2024
PubMed
概括

这项研究引入了一种有效的方法,用于在多重蛋白质成像中选择最小标记子集. 这种方法可以预测比目前在单个组织样本中可测量的更大一组蛋白质标记物.

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相关概念视频

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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