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Updated: Jul 4, 2025

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling
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Published on: March 20, 2018

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Circ0087385通过上调CYP1A1的调节促进了类烯诱导的肺癌发展的DNA损伤

Nan Zhang1,2, Miaoyun Qiu1,2, Shuwei Yao2

  • 1The Key Laboratory of Advanced Interdisciplinary Studies, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 511436, China.

Toxicological sciences : an official journal of the Society of Toxicology
|February 4, 2024
PubMed
概括

环境中的基因毒性化学物质可以改变表观遗传学. 这项研究揭示了一个圆形的RNA,circ0087385,通过激活CYP1A1,通过激活CYP1A1,促进DNA损伤和肺癌的进展,为化学致癌提供了新的见解.

关键词:
造成的DNA损伤是DNA损伤.癌症发生的原因是致癌.圆形的RNARNA是一个圆形的RNA.肺癌是一种肺癌.恶性转变的恶性转变

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