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最近的洞察力基于草本生物活性的新方法治疗慢性肠道炎症疾病治疗方法

Ranjit K Harwansh¹, Sonia Chauhan^1,2, Rohitas Deshmukh¹

¹Institute of Pharmaceutical Research, GLA University, Mathura, 281406, India.

Current pharmaceutical biotechnology

|February 4, 2024

概括

炎症性肠病 (IBD) 是一个日益严重的全球健康问题. 草药化合物由于其抗炎和抗氧化特性,对治疗IBD充满希望,为传统治疗提供了替代方案.

科学领域:

胃肠病学和肝病学胃肠学和肝病学
药理学和制药科学药理学和制药科学
自然产品化学自然产品化学

背景情况:

炎症性肠病 (IBD) 是一种慢性,危及生命的胃肠道疾病,其全球流行率越来越高.
IBD显著影响患者的生活方式,增加结肠癌的风险,并造成巨大的经济负担.
目前的IBD治疗有局限性,包括有效性有限,耐药性,副作用和高成本.

研究的目的:

审查和识别具有抗炎性能的有力草本生物活性物质,用于管理IBD.
探索天然产品作为IBD的潜在治疗剂,解决传统医学的局限性.
突出植物化合物在IBD管理中的作用及其作用机制.

主要方法:

在主要的科学数据库 (Science Direct,PubMed,Google,Scopus) 中进行了全面的文献搜索.
选和分析了研究,重点是之前发表的审查文章,确定草药植物性抗炎剂.
已确定并编制了具有针对IBD的有效性报告的杰出草药生物活性.

主要成果:

一些草本生物活性物质,包括黄素,白醇,酸,西利宾和柏柏林,已证明对IBD有效.
这些天然化合物具有显著的抗炎和抗氧化特性.
草药向关键酶,调节参与IBD病原发生的炎症媒介.

结论:

草本生物活性物是治疗炎症性肠病的有希望的候选药物.
自然产品为传统IBD治疗提供了可行的替代或补充方法.
未来的研究可能将重点放在新型药物输送系统上,以提高草药在IBD管理中的有效性.

关键词:

炎症性肠病是一种炎症性肠病.大肠癌.结肠癌.胃肠道的胃肠道是什么草本生物活性的植物.免疫反应的免疫反应.风险因素的风险因素是什么

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