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针对性局部麻醉:一种新的缓释Fe3O4-利多卡因-PLGA微球,具有磁性准功能

Ling-Xi Zheng1, Qian Yu1, Qiang Li2

  • 1Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China.

Journal of anesthesia
|February 4, 2024
PubMed
概括

具有铁氧化物 (Fe3O4) 的磁性响应的利多卡因微球提供了长时间的术后疼痛缓解. 一个外部磁场将这些微球固定起来,减少扩散,增强向的神经阻塞,延长止痛效果.

关键词:
局部麻醉剂 局部麻醉剂长效的止痛药是一种长效的止痛药.磁性吸引力是一种磁性吸引力.缓解释放的缓慢释放超偏磁性铁氧化物纳米粒子

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Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
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