使用ART获得的活产后的回报率:频率和决定因素
Alessia Limena1,2, Marco Reschini3, Dalila Invernici4
1Department of Clinical Sciences and Community Health, Università Degli Studi Di Milano, Milan, Italy. alessia.limena@unimi.it.
Archives of gynecology and obstetrics
|February 4, 2024
概括
大约50%的夫妇在第一次成功的试管婴儿怀孕后重生第二个孩子. 影响这一决定的因素包括年龄和试管婴儿周期特征,突出了个性化生育护理的需要.
科学领域:
- 生殖医学 生殖医学
- 不孕症治疗 不孕症治疗
- 辅助生殖技术 (ART) 是一种辅助生殖技术.
背景情况:
- 许多为第一个孩子进行体外受精 (IVF) 的夫妇希望有第二个孩子.
- 了解后续怀孕返回ART中心的回归率对于计划生育和资源分配至关重要.
研究的目的:
- 为了确定夫妇在第一次活产后为第二个孩子返回ART中心的频率.
- 通过ART确定影响第二个孩子的决定的因素.
主要方法:
- 进行了一项回顾性单心队列研究.
- 包括那些通过试管婴儿实现了第一次活产的妇女.
- 该研究评估了五年内第二个孩子的回归率,并分析了这一率的决定因素.
主要成果:
- 在374名妇女中,188名 (50%) 回到了第二个孩子. 在那些没有回来的人中,原因包括自然受孕 (34%),放弃父母身份 (36%) 或不成功的自然尝试 (30%).
- 不再接受ART的女性年龄较大 (中位数为36岁与34岁),更有可能通过新鲜胚胎移植怀孕他们的第一个孩子 (75%与59%).
- 这些妇女还获得了更多的卵细胞 (中位数为10对9) 和更少的冷胚胎 (27%对52%).
结论:
- 在成功的ART辅助第一个分娩后,很大一部分夫妇寻求第二个孩子.
- 临床管理应考虑预期孩子的数量,因为这会影响治疗策略和患者咨询.
- 年龄和特定的试管婴儿周期参数,如胚胎冷保存,在随后的家庭建设决策中发挥作用.
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