肺部地面玻璃结节患者的CT成像特征,这些患者有升级的手术内冷病理
Hongya Wang1, Aiping Chen2, Kun Wang1
1Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.
Discover oncology
|February 4, 2024
概括
在肺癌手术中,冷截面病理 (FS) 的准确性是有限的. CT成像功能可以预测FS升级,帮助外科医生避免不足的边缘,并改善患者的结果.
科学领域:
- 胸部外科手术 胸部外科手术
- 病理学 病理学 病理学
- 放射学 放射学是一门学科.
背景情况:
- 术内冷部位病理学 (FS) 对于指导肺癌手术至关重要.
- 然而,FS的准确性有限,可能导致低估瘤阶段和不充分的外科手术边缘.
研究的目的:
- 为了识别与升级FS诊断相关的计算机断层扫描 (CT) 成像特征.
- 开发一个预测模型来识别患有FS低估风险的患者.
主要方法:
- 从2019年1月至12月对860名肺部手术患者的回顾性分析.
- 对FS和最终的甲固定嵌切口 (FP) 诊断的比较,根据差异对患者进行分类.
- 使用CT成像特征预测FS升级的物流回归模型的开发,通过ROC曲线分析验证.
主要成果:
- FS和FP之间的一致率为84.19%.
- 在非侵入性腺癌 (IAC) 的FS诊断中,很大一部分 (26.67%) 被升级为IAC.
- 像巩固瘤比率 (CTR) ≤0.5和较小的结节直径等CT特征与FS低估有关. 预测模型实现了0.785.5的AUC.
结论:
- 电脑图像扫描可以有效地识别在手术内FS期间患上升级风险的患者.
- 利用CT特征可以帮助手术决策,并可能改善手术边缘评估.
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