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Updated: Jul 4, 2025

Expanding the Comprehension of the Tumor Microenvironment using Mass Spectrometry Imaging of Formalin-Fixed and Paraffin-Embedded Tissue Samples
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质谱成像方法可用于可视化瘤异质性

Kyle D Duncan1, Helena Pětrošová2, Julian J Lum3

  • 1Department of Chemistry, Vancouver Island University, Nanaimo, British Columbia, Canada; Department of Chemistry, University of Victoria, Victoria, British Columbia, Canada.

Current opinion in biotechnology
|February 4, 2024
PubMed
概括

质谱成像 (MSI) 揭示了瘤内的分子差异,有助于理解癌细胞行为和微环境. 这项技术在现场绘制生物分子图,以获得更深入的生物学见解.

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Quantitative Multispectral Analysis Following Fluorescent Tissue Transplant for Visualization of Cell Origins, Types, and Interactions

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相关概念视频

Mass Spectrometry: Complex Analysis01:21

Mass Spectrometry: Complex Analysis

Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
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