基于规模的度测量和深度学习方法,用于分析COVID-19受试者在康复期间和之后心肺呼吸系统控制系统的动态特征
Madini O Alassafi1, Wajid Aziz2, Rayed AlGhamdi1
1Faculty of Computing and Information Technology, King Abdulaziz University, Jeddah, Saudi Arabia.
Computers in biology and medicine
|February 4, 2024
概括
这项研究表明,使用基于尺度的 (SBE) 和深度学习分析氧和度变化 (OSV) 信号可以区分COVID-19疾病和康复. 多尺度模糊 (MFE) 与辐射基函数网络 (RBFN) 在分类这些心肺呼吸信号方面取得了高准确性.
科学领域:
- 生理学 生理学 生理学
- 生物医学工程 生物医学工程
- 数据科学数据科学数据科学
背景情况:
- COVID-19 (冠状病毒疾病2019) 主要影响呼吸系统,但可能导致心肺呼吸系统并发症.
- 在COVID-19患者中评估心肺控制系统 (CRCS) 动态对于临床决策至关重要.
- 基于的复杂度测量提供了分析生理信号的新方法,例如氧和度变化 (OSV).
研究的目的:
- 使用基于尺度的 (SBE) 方法来描述COVID-19疾病和恢复期间OSV信号的动态复杂性.
- 应用机器学习 (ML) 和深度学习 (DL) 技术来根据SBE特征对OSV信号进行分类.
- 评估不同SBE措施和DL模型在检测COVID-19患者CRCS功能障碍方面的有效性.
主要方法:
- 采集了44名COVID-19患者在活跃感染期间和康复后两个月使用Beurer PO-80脉冲氧计收集的非侵入性OSV和脉冲率数据.
- 应用了SBE方法,包括多尺度 (MSE),多尺度顺序 (MPE) 和多尺度模糊 (MFE),以描述OSV信号复杂性.
- 利用深度学习模型,特别是辐射基函数网络 (RBFN) 和带动态延迟算法 (RBFNDDA) 的 RBFN,将 SBE 测量作为分类的输入特征.
主要成果:
- 基于规模的分析显示,与康复阶段相比,在活跃的COVID-19感染期间,OSV信号复杂性减少.
- 与RBFN结合的多尺度模糊 (MFE) 显示出优异的分类性能,达到0.84的灵敏度,0.70的特异性和0.77.7的曲线下面面积 (AUC).
- 该分类模型有效地区分了来自COVID-19疾病和康复期的OSV数据.
结论:
- 在COVID-19期间,SBE测量,特别是MFE,对于量化心肺呼吸系统动态变化是有效的.
- 将SBE措施与RBFN等深度学习模型的整合提供了一个强大的方法来分类与COVID-19相关的OSV信号.
- 这种方法有助于识别COVID-19患者的心肺控制系统功能障碍,并可以支持疾病和康复期间的临床评估.
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