休息心率的时间变化和患糖尿病的风险
Mi Kyoung Son1, Kyoungho Lee1, Hyun-Young Park2
1Division of Population Health Research, Department of Precision Medicine, Korea National Institute of Health, Cheongju, Korea.
Diabetes & metabolism journal
|February 4, 2024
概括
静止心率 (RHR) 变化 (∆RHR) 的降低与降低糖尿病 (DM) 风险有关. ∆RHR的增加与更高的DM风险有关,但仅在女性身上.
科学领域:
- 心血管流行病学心血管流行病学
- 代谢性疾病研究研究
- 纵向队列研究 纵向队列研究
背景情况:
- 休息心率 (RHR) 和随时间的变化可能会影响糖尿病 (DM) 风险.
- 调查RHR动态和DM发病率之间的性别相关性至关重要.
研究的目的:
- 检查时间变化的RHR,RHR变化 (∆RHR) 和发展DM的风险之间的关系.
- 为了确定这些关联是否在男性和女性之间有所不同.
主要方法:
- 对8,392名没有DM或心房动/动的参与者进行前性队列研究.
- 两年一次的RHR测量更新了时间变化的∆RHR,平均随访时间为12.3年.
- 统计分析根据RHR水平和∆RHR类别评估了DM发病率.
主要成果:
- 较高的RHR (≥80 bpm) 与男性和女性的DM发病率增加有显著的关联.
- ∆RHR的下降 (≥5bpm下降) 与男性和女性的DM风险显著降低相关.
- ∆RHR的增加 (每小时≥5步的增加) 仅在女性中与显著更高的DM风险有关.
结论:
- 减少RHR变化 (∆RHR) 与降低糖尿病风险有关.
- 增加RHR变化 (∆RHR) 与糖尿病风险增加有关,特别是在女性中.
- 对RHR动态的性别特定监测可能有助于预测糖尿病风险.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.4K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.4K
Psychoneuroimmunology: Diabetes and Cancer
29
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
29
Diabetes: Symptoms, Diagnosis, and Complications
544
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
544
Pathophysiology of Diabetes
940
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
940
Diabetes Mellitus: Overview and Type I Subtype
2.6K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.6K
Factors Influencing Heart Rate
2.7K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
2.7K


