暴露于空气污染和心脏代谢风险
Sanjay Rajagopalan1, Robert D Brook2, Pedro R V O Salerno1
1University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
The lancet. Diabetes & endocrinology
|February 4, 2024
概括
空气污染,特别是细颗粒物 (PM2.5),与全球20%的2型糖尿病病例有关. 本综述探讨了这一可预防的公共卫生风险的证据和解决方案.
科学领域:
- 环境健康 环境健康
- 心血管研究研究心血管研究
- 代谢性疾病流行病学
背景情况:
- 长期暴露于细颗粒物 (PM2.5) 是一个重要的全球健康问题.
- 空气污染水平超过了世卫组织对世界上大多数人口的指导方针.
- 越来越需要了解空气污染与心脏代谢疾病之间的联系.
研究的目的:
- 提供连接空气污染和心脏代谢风险的流行病学证据的最新摘要.
- 阐明这种关联背后的机械路径.
- 概述干预措施,以减轻空气污染暴露的公共健康风险.
主要方法:
- 关于空气污染和心脏代谢疾病的当前流行病学研究的审查.
- 对颗粒物生物效应的机械研究进行分析.
- 综合个人,社区和政策层面干预的证据.
主要成果:
- 据估计,全球约20%的2型糖尿病病例归因于长期暴露于PM2.5.
- 证据强烈地将空气污染暴露与心脏代谢风险增加联系在一起.
- 为了减轻这种风险,存在多种干预策略.
结论:
- 空气污染是心脏代谢疾病的主要可改变的风险因素,包括2型糖尿病.
- 需要采用涉及个人,社区和政策干预的多方面的方法.
- 解决空气污染问题对于全球公共卫生和减缓气候变化至关重要.
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