传统中医在调节巨细胞两极分化的过程中,在炎症性疾病的免疫反应中发挥作用
Shiyu Chen1, Jiuseng Zeng1, Rui Li2
1State Key Laboratory of Southwestern Chinese Medicine Resources, Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, PR China.
Journal of ethnopharmacology
|February 4, 2024
概括
传统中医药 (TCM) 通过调节巨细胞极化和代谢重编程,有效治疗炎症性疾病. 这次审查巩固了TCM机制,有助于开发新的天然抗炎药物.
科学领域:
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
- 自然产品 自然产品
背景情况:
- 传统中医药 (TCM) 显示出强大的抗炎作用.
- 这些效应通过调节巨细胞两极分化和代谢重编程来调节.
- 巨细胞两极分化是炎症性疾病的一个关键机制.
研究的目的:
- 审查炎症疾病中巨细胞两极分化的致病机制.
- 要总结TCM对巨细胞两极分化的作用.
- 引导自然抗炎药物的开发.
主要方法:
- 在PubMed和谷歌学者的综合文献评论.
- 关键词: "巨分化", "中国传统医药", "炎症", "天然产品".
- 对最近有关TCM和炎症的出版物的分析.
主要成果:
- 113种TCM (成分,提取物,处方) 显示具有抗炎作用.
- TCMs调节巨细胞极化和代谢重编程的关键途径.
- 已识别的TCM为炎症性疾病提供治疗潜力.
结论:
- 巨细胞两极分化和代谢重编程在炎症治疗中至关重要.
- 在调节巨细胞极化方面,TCM提供了多路径,多目标的优势.
- 这一审查支持基于TCM的天然抗炎药物开发.
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