智利专家小组使用德尔菲技术进行胃癌的初级和二级预防的智利共识
Óscar Corsi Sotelo1, Margarita Pizarro Rojas1, Antonio Rollán Rodríguez2
1Departamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Gastroenterologia y hepatologia
|February 4, 2024
概括
这项研究建议对35至44岁的个人进行H. pylori检测和治疗,以预防初级胃癌. 对于45岁及以上的人来说,建议采用H. pylori和内镜联合策略进行初级和二级预防.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 胃癌 (GC) 是智利和LAC地区癌症死亡的主要原因.
- 杆菌 (H. pylori) 是主要的致癌物,其根除可以减少GC的发生率.
- 目前的LAC指南缺乏对H. pylori的大规模查和早期GC检测.
研究的目的:
- 为智利的无症状,标准风险人群制定初级和二级胃癌预防建议.
- 根据年龄组分层预防策略.
- 为了解决LAC地区缺乏实施的查计划的问题.
主要方法:
- 两轮的德尔菲小组协商一致,其中包括智利专家.
- 举行了研讨会和研讨会,讨论并就预防策略达成一致.
- 根据年龄组对人口进行分层划分,以提供量身定制的建议.
主要成果:
- 对于16-34岁年龄组的H. pylori检测/治疗或EGD没有共识.
- 推H. pylori的非侵入性检测和治疗,对35至44岁的年龄组进行治愈测试.
- 建议结合H. pylori检测/治疗,非侵入性生物标志物和EGD与悉尼议定书活检,适用于≥45岁的年龄组,以OLGA为基础的监测.
结论:
- 为35-44岁年龄组的初级预防提出了H. pylori的"测试和治疗"策略.
- 在≥45岁的年龄组中,建议采用H. pylori管理和内镜查的联合策略来进行初级和二级预防.
- 这些拟议的战略可适应其他拉美国家.
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