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一个系统的回顾患者衍生瘤器官的产生从恶性溢出
Sofie Seghers1, Maxim Le Compte2, Jeroen M H Hendriks3
1Department of Oncology, Antwerp University Hospital, Edegem, Belgium; Center for Oncological Research (CORE), University of Antwerp, Wilrijk, Belgium.
Critical reviews in oncology/hematology
|February 4, 2024
概括
恶性排泄物 (ME) 是患者衍生瘤器官 (PDTO) 的可行来源,提供一种最小侵入性的替代方案. 这篇评论强调了它们在药物查和个性化医疗方面的潜力.
科学领域:
- 在瘤学瘤学.
- 再生医学是一种再生医学.
- 生物技术是生物技术.
背景情况:
- 恶性排泄物 (ME) 是患者衍生瘤器官 (PDTO) 的未充分利用的来源.
- PDTO对于个性化癌症治疗和药物开发至关重要.
- 目前的有机体生成主要依赖于手术切除标本或活检.
结论:
- 恶性排泄物是产生患者衍生瘤器官的可靠和可访问的来源.
- ME-PDTO对临床前药物查和推进个性化瘤学具有重大前景.
- 建议进行进一步的研究,以优化培养方案,并充分实现ME-PDTOs的临床潜力.
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