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在人类TK6细胞中评估氧化的弱基因毒性

Xilin Li1, Yuan Le1, Yuxi Li1

  • 1Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA.

Toxicology letters
|February 4, 2024
PubMed
概括

氧化chloroquine (HCQ) 在人类细胞中没有突变性. 然而,长时间暴露于HCQ诱导了DNA损伤和亡,为基因毒性风险评估提供了信息.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.氨酸 (Chloroquine) 是一种化学物质.染色体损伤 染色体损伤造成的DNA损伤是DNA损伤.氧化chloroquine 的使用情况.在TK6细胞中,

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