手术前的甲状腺激素替代与腹部重大手术后的外科并发症的关联
Catherine T Haring1, Molly E Heft Neal2, Craig A Jaffe3
1Department of Otolaryngology-Head and Neck Surgery, The Ohio State University, Columbus, OH, USA.
American journal of surgery
|February 4, 2024
概括
在重大腹部手术前接受甲状腺激素替代治疗的患者面临严重发病和更长时间住院的风险增加. 这一发现强调了手术前对接受重大腹部手术的患者进行仔细评估的重要性.
科学领域:
- 手术结果研究研究.
- 内分泌学 在内分泌学.
- 患者安全 患者安全
背景情况:
- 在接受手术的患者中,甲状腺激素替代是常见的.
- 手术前使用甲状腺激素对手术并发症的影响尚未完全理解.
研究的目的:
- 调查手术前甲状腺激素替代和腹部大手术后并发症之间的关联.
- 为了确定与手术患者使用甲状腺激素相关的风险.
主要方法:
- 2700名接受腹部重大手术的患者的回顾性病例系列.
- 分析了长达10年的密歇根外科质量协作 (MSQC) 数据.
- 多变量分析以控制已确立的手术发病率预测因素.
主要成果:
- 手术前的甲状腺激素替代与严重发病风险增加1.5倍有关.
- 接受甲状腺置换治疗的患者患严重败血症的风险高出1.7倍.
- 甲状腺激素的使用与更长的逗留时间和更高的开放手术可能性有关.
结论:
- 手术前的甲状腺激素替代是手术后发病率的独立预测因素.
- 甲状腺激素的使用与主要腹部手术后逗留时间的增加有关.
- 进一步的研究可能会探索优化外科手术期间甲状腺激素管理.
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