全球人口患病率和亚诊断性胃肠道症状的影响
Olafur S Palsson1, Jan Tack2, Douglas A Drossman3
1University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
很大一部分成年人经历频繁的胃肠道症状,但不符合完整的诊断标准. 这一"亚诊断"组报告生活质量下降和医疗保健需求增加,突出了对这些人的护理差距.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 罗马基金会全球流行病学研究 (RFGES) 发现,26个国家的40.3%的成年人符合肠-大脑相互作用 (DGBI) 障碍的标准.
- 相当数量的个人可能会经历频繁的胃肠道症状,但不符合DGBI的全部诊断标准,可能面临重大负担.
研究的目的:
- 调查患有亚诊断性胃肠道症状的个体的流行率和人口分布.
- 评估这些症状对生活质量 (QoL),生活功能和医疗保健利用的影响.
主要方法:
- 分析RFGES数据,包括罗马四号诊断问卷.
- 包括有关QOL,心理困扰,工作生产力和医疗保健使用问题的问题.
主要成果:
- 在没有有机胃肠道疾病的50 033名成年人中,25.3%属于亚诊断组.
- 与非GI组相比,亚诊断组显示显著降低了QOL,增加了心理和体质症状,以及更高的医疗利用率.
- 患病率在全球范围内有所不同,中东 (30.5%) 和北美 (22.2%) 的患病率更高,在男性和年轻人中更为常见.
结论:
- 大约四分之一没有被诊断为DGBI的成年人经常出现胃肠道症状.
- 这个亚诊断组表现出降低了QOL和增加了医疗保健需求,这表明需要有针对性的干预和自我管理支持.
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