相关实验视频

Updated: Jul 4, 2025

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

在沙特阿拉伯,高尿血与肝功能的患病率和相关性:一项大型横截面研究

Abdulaziz Almuqrin¹, Yazeed Abdullah Alshuweishi¹, Mohammed Alfaifi²

¹From the Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

Annals of Saudi medicine

|February 5, 2024

概括

在沙特阿拉伯,高尿路血是很常见的,影响到人口的17.3%. 尿酸水平升高与肝功能受损的标志物如ALT,AST和总胆红素相关.

科学领域:

临床化学临床化学
公共卫生公共卫生
肝病学肝病学是一种肝病学.

背景情况:

高尿路血是慢性疾病的已知危险因素.
有限的数据存在于沙特阿拉伯的hyperuricemia患病率及其与肝功能的联系.

研究的目的:

为了确定沙特人口中高尿血病的患病率.
调查尿酸水平与肝功能参数之间的关联.
评估风险指标,将hyperuricemia和肝功能联系在一起.

主要方法:

来自沙特人口数据库的大型实验室数据的回顾性,横截面分析.
受试者 (n=13,314) 根据尿酸 (UA) 水平分层:高尿酸性,正常尿酸性和高尿酸性.
研究了UA与肝酶的相关性:亚氨酸转氨酶 (ALT),阿斯巴酸转移酶 (AST),酸酸酶 (ALP) 和总 bilirubin (TB).

主要成果:

高尿路血的患病率为17.3% (20.3%的男性,15.1%的女性).
在血清UA水平与ALT,AST和结核病之间观察到正相关性.
升高的ALT,AST和结核病显著增加了高尿血的风险,显示出良好的分辨能力.

结论:

在沙特阿拉伯,高尿路血症非常普遍.
超尿血和肝功能受损之间存在显著的关联.
需要进一步的研究,包括前性研究,以了解潜在的机制.

更多相关视频

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Published on: October 3, 2020

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method

Published on: October 23, 2018

相关概念视频

Diseases of the Liver and Gallbladder

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...

Factors Affecting Renal Clearance: Renal Impairment

Factors Affecting Renal Clearance: Renal Impairment

Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...

Ultrasound II: Endoscopic Ultrasound and FibroScan

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):