在老年成人癌症幸存者中,大麻的感知和使用模式
Margaret C Fahey1, Kyle J Walters1,2, Andreana M Benitez3
1Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA.
Journal of aging and health
|February 5, 2024
概括
在没有合法大麻的州的老年癌症幸存者通常使用它来治疗疼痛和失眠. 然而,很少有人与他们的医疗保健提供者讨论使用大麻的问题,这突出了关于这种治疗选择的沟通缺口.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 老年癌症幸存者面临着独特的挑战,包括症状管理和生活质量.
- 大麻越来越多地被探索治疗益处,但在非法律状态的老年癌症患者中使用大麻的研究不足.
- 了解感知和使用模式对于明智的患者护理和政策制定至关重要.
研究的目的:
- 描述性地评估老年成人癌症幸存者 (65+) 中的大麻感知.
- 在一个缺乏合法大麻市场的州内,在这个人口中识别大麻使用模式.
- 探索癌症幸存者的使用原因和消费方式.
主要方法:
- 使用加权流行率估计的横截面研究.
- 数据来自524名老年癌症幸存者 (65岁以上) 在国家癌症研究所指定中心收集的数据.
- 对大麻感知和使用模式的描述性分析.
主要成果:
- 近一半 (46%) 的老年癌症幸存者报告说曾经使用过大麻,18%的人在诊断后使用过大麻,10%的人目前使用大麻.
- 疼痛 (44%) 和失眠 (43%) 是诊断后大麻使用的主要原因,主要是通过吸烟 (40%).
- 只有8%的参与者与他们的医疗保健提供者讨论了大麻,很少有人 (<3%) 报告了不良影响.
结论:
- 老年癌症幸存者利用大麻来治疗症状,即使是在没有合法进入的地区.
- 老年癌症幸存者和提供者之间存在着关于大麻使用的重大沟通差距.
- 需要进行进一步的研究,以探索针对这一群体的安全和有效的基于大麻的干预措施.
相关概念视频
Cancer Survival Analysis
348
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
348
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
278
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
Two synthetic agonists of THC,...
278
Longitudinal Research
12.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.0K
Psychoneuroimmunology: Diabetes and Cancer
29
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
29
Treatment Resistant Cancers
3.3K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.3K
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K


