在患有慢性脏病的患者中,血液透析诱导的时间干扰和时间型分布
Patrícia Pereira Nunes1, Caroline Meneses Resende1, Ellen Dayanne Barros Silva1
1Faculty of Medicine, Federal University of Alagoas, Maceió, Brazil.
Chronobiology international
|February 5, 2024
概括
血液透析在40.6%的慢性病患者中破坏昼夜节律,影响他们的生活质量. 早晨的时刻型是普遍存在的,与一般人群有很大的差异.
科学领域:
- 时间生物学 时间生物学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 睡眠医学 睡眠医学
背景情况:
- 循环节律障碍在慢性病 (CKD) 患者中很常见.
- 这些干扰与不良健康结果有关,需要进一步调查.
- 血液透析对昼夜时间的影响及其后果仍未得到充分研究.
研究的目的:
- 为了研究血液透析诱导的慢性干扰 (HIC) 在CKD患者.
- 为了确定血液透析患者之间的时间型分布.
- 评估HIC,时间型,睡眠质量和生活质量 (QoL) 之间的关联.
主要方法:
- 一项涉及165名血液透析患者的横截面研究.
- 使用的验证问卷:MEQ,MCQT (修改为HIC),KDQOL-SF,ESS,PSQI和10-CS.
- 统计分析以评估HIC流行率,时间型分布以及与QoL和睡眠的关联.
主要成果:
- 血液透析诱导的慢性干扰 (HIC) 在40.6%的患者中存在.
- 在CKD患者中,早晨的时刻型是普遍存在的 (69%),与一般人群显著不同.
- HIC和时间型与生活质量 (QoL) 的特定领域有关,但与睡眠质量无关.
结论:
- 血液透析诱导的慢性干扰 (HIC) 是CKD患者的一个重要问题.
- 在这个人群中,早晨时刻型的流行值得注意.
- 血液透析患者的循环节律变化对他们的整体生活质量 (QoL) 有影响.
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