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相关概念视频

Oxidation of Alcohols02:37

Oxidation of Alcohols

13.1K
In this lesson, the oxidation of alcohols is discussed in depth. The various reagents used for oxidation of primary and secondary alcohols are detailed, and their mechanism of action is provided.
The process of oxidation in a chemical reaction is observed in any of the three forms:
13.1K
Radical Substitution: Allylic Chlorination01:31

Radical Substitution: Allylic Chlorination

2.3K
Typically, when alkenes react with halogens at low temperatures, an addition reaction occurs. However, upon increasing the temperature or under reaction conditions that form radicals, providing a low but steady concentration of halogen radicals, allylic substitution reaction is favored. This is because allylic hydrogens are very reactive as the formed intermediate is resonance stabilized. For example, when propene is treated with chlorine in the gas phase at 400 °C, it undergoes allylic...
2.3K
Oxidative Cleavage of Alkenes: Ozonolysis01:46

Oxidative Cleavage of Alkenes: Ozonolysis

10.4K
In ozonolysis, ozone is used to cleave a carbon–carbon double bond to form aldehydes and ketones, or carboxylic acids, depending on the work-up.
Ozone is a symmetrical bent molecule stabilized by a resonance structure.
10.4K
Oxidation of Phenols to Quinones01:17

Oxidation of Phenols to Quinones

3.0K
In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
3.0K
Redox Reactions01:24

Redox Reactions

55.7K
Oxidation-reduction or redox reactions involve the transfer of electrons from one molecule or atom to another. When an atom gains an electron, another atom must lose an electron, meaning oxidation and reduction must occur together. Since the redox occurs in pairs, the atom that gets oxidized is also called the reducing agent or reductant, and the atom that is reduced is also called the oxidizing agent or oxidant. A straightforward way to remember the definitions of oxidation and reduction is...
55.7K
Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids02:04

Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids

5.8K
Diols are compounds with two hydroxyl groups. In addition to syn dihydroxylation, diols can also be synthesized through the process of anti dihydroxylation. The process involves treating an alkene with a peroxycarboxylic acid to form an epoxide. Epoxides are highly strained three-membered rings with oxygen and two carbons occupying the corners of an equilateral triangle. This step is followed by ring-opening of the epoxide in the presence of an aqueous acid to give a trans diol.
5.8K

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相关实验视频

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Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
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Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

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最近氧化化技术的进展.

Hai-Lei Cui1

  • 1Laboratory of Asymmetric Synthesis, College of Chemistry and Environmental Engineering, Chongqing University of Arts and Sciences, 319 Honghe Ave., Yongchuan, Chongqing, 402160, PR China. cuihailei616@163.com.

Organic & biomolecular chemistry
|February 5, 2024
PubMed
概括

开发绿色氧化化方法对于有机化物至关重要. 本综述涵盖了2013-2023年间从可访问的化物和氧化剂中现场生成的实际化物种.

科学领域:

  • 有机化学 有机化学
  • 合成化学 合成化学

背景情况:

  • 有机化物广泛应用于各种研究领域.
  • 需要有效,实用和环保的化技术.

研究的目的:

  • 审查最近氧化化方法的进展.
  • 突出利用易于获得的化物和氧化剂用于现场生成活性化物种的方法.

主要方法:

  • 专注于氧化化策略.
  • 使用可访问的化物 (例如NaCl,HCl,KCl,CHCl3) 和各种氧化剂.
  • 概述了2013年至2023年间开发的方法.

主要成果:

  • 氧化化提供了诸如使用廉价和安全的原料等优势.
  • 这种方法确保了的良好原子经济.
  • 可以使用各种氧化剂,提供灵活性.

结论:

  • 氧化化是一种合成有机化物的有吸引力的策略.
  • 该综述提供了关于该领域最近发展情况的全面概述.
  • 这些方法是实用的,具有成本效益,并与绿色化学原则保持一致.

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