病因学,微生物分离物和抗生素敏感性在住院患者的耐火性耳耳周周状炎:一个10年的回顾性研究
Xiuwen Zhang1, Yibo Zhang2,3,4, Chen Pu5
1Department of Pharmacy, Eye & ENT Hospital, Fudan University, Shanghai, People's Republic of China.
Infection and drug resistance
|February 5, 2024
概括
手术后的感染是耳环周心炎的主要原因,通常涉及Pseudomonas aeruginosa. 虽然万科米辛和阿米卡辛表现出很高的敏感性,但随着诺基诺抗性的增加,需要探索这种耳部感染的新治疗策略.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 耳垂炎是一种影响耳朵软骨的感染.
- 了解其原因,微生物罪祸首和抗生素耐药性模式对于有效管理至关重要.
研究的目的:
- 调查耳环周周炎的病因,微生物特征,抗生素敏感性和患者结局.
- 识别致病原体的趋势及其随时间的耐药性模式.
主要方法:
- 在2013年1月至2022年12月期间,对被诊断患有耳膜周心炎的住院患者进行了单一中心的回顾性研究.
- 对患者人口统计,感染源,微生物分离物,抗生素敏感性测试和治疗结果的分析.
主要成果:
- 手术后感染是主要原因 (37.8%),其次是创伤 (18.1%). Pseudomonas aeruginosa 是最常见的隔离物 (49.2%).
- 在术后病例中,真菌感染更为普遍. 格拉姆阴性细菌和真菌在2018-2022年间呈现出日益增长的趋势.
- 观察到对万科米辛和阿米卡辛的高度敏感性,但诺基诺隆耐药性正在上升,特别是在Pseudomonas aeruginosa.
结论:
- 耳膜周边膜炎经常源于阳性 (术后) 原因.
- 针对Pseudomonas aeruginosa的实证治疗通常是合适的,但增加诺基诺隆耐药性需要考虑替代策略.
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