绘制肺癌中铁亡研究的过程:从文献计量分析的见解
Huatao Zhou1, Yu Mao2, Zijing Zhou3
1Department of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Middle Renmin Road 139, Changsha, 410011, China.
Heliyon
|February 5, 2024
概括
这项研究分析了肺癌中的铁灭研究,揭示了指数增长和生物标志物和治疗耐药性等关键主题. 新兴领域包括免疫微环境,建议新的治疗策略.
科学领域:
- 在瘤学瘤学.
- 生物化学 生物化学
- 细胞生物学 细胞生物学
背景情况:
- 肺癌是全球癌症死亡的主要原因之一.
- 铁灭,一种新的细胞死亡途径,为肺癌提供了一个有前途的治疗标.
- 了解肺癌铁亡的研究趋势对于开发创新的治疗方法至关重要.
研究的目的:
- 对肺癌中铁亡的研究进行全面的图书统计分析.
- 确定这一领域的关键研究趋势,有影响力的出版物和新兴的前沿领域.
- 绘制全球研究格局和合作网络的地图.
主要方法:
- 在2014年至2023年10月期间发表的488篇文章的图书统计分析.
- 使用了VOSviewer,CiteSpace,以及R包"bibliometrix"的功能.
- 来自Web of Science核心集合的数据,包括用于主题细分的集群分析.
主要成果:
- 从2019年到2023年观察到出版物的显著指数增长.
- 确定了四个主要研究主题:肺癌特征,生物标志物识别和预后,细胞死亡机制和代谢调节,以及癌症干细胞和治疗抵抗.
- 新兴研究热点包括免疫微环境和线粒体功能障碍;斯科特·J·迪克森的工作得到了高度引用.
结论:
- 铁亡是一个快速增长的研究领域,对肺癌至关重要.
- 确定的主题和新兴主题为未来的研究方向提供了路线图.
- 这项分析支持开发新的铁灭向疗法,以改善肺癌治疗结果.
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