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Updated: Jul 4, 2025

Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells
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新型的oxicam非类固醇化合物XK01通过抑制RAW264.7巨细胞中的NF-κB和MAPK通路来减轻炎症

Jixiang Wang1, Jiawang Tan1, Qianmei Hu1

  • 1The Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, and Department of Pharmacy, School of Medicine, Hunan Normal University, Hunan, 410013, China.

Heliyon
|February 5, 2024
PubMed
概括

一种新型的非类固醇抗炎药物XK01有效降低了氧化物和细胞因子等炎症标志物. 它向循环氧化酶-2 (COX-2) 并抑制关键的炎症通路,提供潜在的治疗益处.

关键词:
循环氧化基因酶 (Cyclooxygenase) 是一种炎症 炎症是一种炎症.巨细胞是一个巨细胞.通过NF-κB信号通路传递信号.氧化是一种氧化.

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