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在COVID-19大流行期间患有黄金杆菌菌菌病的患者的死亡率模式:预测因素和见解

Arash Abdollahi¹, Marzieh Nojomi², Yeganeh Karimi¹

¹Medical Doctor, Iran University of Medical Sciences, Tehran, Iran.

|February 5, 2024

概括

黄金杆菌菌菌病 (SAB) 死亡率仍然很高,特别是在老年患者和被送往重症监护室的患者中. 患者的年龄和性别等因素,而不是抗生素耐药性,是COVID-19大流行期间死亡率的关键预测因素.

科学领域:

传染性疾病传染性疾病
流行病学流行病学
关键护理医学关键护理医学

背景情况:

黄金杆菌菌菌 (SAB) 构成了重大的公共卫生挑战,其影响可能会因COVID-19大流行而加剧.
了解住院死亡率和SAB相关风险因素对于有效的临床管理至关重要.

研究的目的:

为了确定COVID-19大流行期间的Staphylococcus aureus bacteremia (SAB) 的医院死亡率.
为了确定此期间与SAB相关的死亡率的相关风险因素.

主要方法:

一项回顾性研究涉及2020年3月至2022年3月期间在伊朗德黑兰一家教学医院的167例SAB病例.
收集患者基线数据,抗生素图和住院死亡结果.
多变量分析以确定死亡率的独立预测因素.

主要成果:

对SAB的整体住院死亡率为41.9%.
60岁以上的患者,社区获得的SAB患者和ICU入院患者的死亡率较高.
虽然一些抗生素耐药性 (西普罗夫洛克萨,甲,硫甲) 显示死亡率较高,但多变量分析确定年龄,性别,ICU入院和细菌源是独立的预测因素,而不是COVID-19共感染或一般抗生素耐药性.

结论:

黄金葡萄球菌 (SAB) 仍然是一个关键的感染,死亡率受到患者人口统计和护理环境的影响.
老年和重症监护室 (ICU) 的入院是死亡率的重要预测因素.
在MRSA患病率高的地区,与患者相关的因素 (年龄,性别) 和护理质量似乎比抗生素耐药性模式更有影响力.

关键词:

抗生素耐药性抗生素耐药性在 COVID-19 疫情中,黄金葡萄球菌黄金葡萄球菌黄金葡萄球菌的细菌病.

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