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Updated: Jul 4, 2025

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异构细胞ATTR Tyr114Cys粉样性病特异性诱导多能干细胞的表征

Kenta Ouchi1, Kaori Isono2, Yuki Ohya2,3

  • 1Department of Clinical Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kumamoto University, 2-2-1 Honjo, Chuo Ward, Kumamoto City, Kumamoto Prefecture, 860-8556, Japan.

Heliyon
|February 5, 2024
PubMed
概括

研究人员生成了患者特异性诱导多能干细胞 (iPS细胞) 来治疗由Tyr114Cys突变引起的遗传性转基因氨基粉症 (ATTRv氨基粉症). 这些iPS细胞为研究这种致命疾病的分子机制提供了一个新的工具.

关键词:
遗传性转基因氨基粉症.转二烯素是一种转二烯素.在Tyr114Cys上使用.iPS 细胞 细胞 iPS 细胞

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