在综合征和非综合征患者中,奥登托基尼囊的复发模式
Tim Van Cleemput1,2, Xander Jackers1,2, Maria Piagkou3
1OMFS IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, KULeuven, Louvain, Belgium.
Journal of maxillofacial and oral surgery
|February 5, 2024
概括
在综合征患者中,特别是那些患有未经避免的基细胞癌综合征 (NBCCS) 患者中,口腔致瘤 (OKC) 更频繁地复发. 综合征患者也有更高的风险发展新的初级OKCs.
科学领域:
- 口腔和牙面部外科手术
- 在瘤学瘤学.
- 遗传学 是一个遗传学.
背景情况:
- 牙原性角囊 (OKC) 以其高的复发率而闻名.
- 了解复发模式和二次OKC的发展对于患者管理至关重要.
研究的目的:
- 为了调查Odontogenic keratocysts (OKCs) 的复发模式.
- 确定综合征和非综合征患者中第二次原发性OKC的发生率.
- 为了比较患有和没有nevoid基底细胞癌综合征 (NBCCS) 的患者之间的这些模式.
主要方法:
- 51名OKC患者 (1998-2021) 的回顾性评估.
- 收集的数据包括人口统计,临床,组织病理学,放射学和治疗细节.
- 随访时间超过3年,以评估复发和新的初级OKC,对NBCCS患者进行单独分析.
主要成果:
- 非综合征性OKC的复发率为15.8%,综合征性OKC的复发率为21.4%.
- 第二次复发发生在8.9%的患者中,第三次发生在1.8%的患者中.
- 在非综合征患者中没有发现第二次原发性OKC,而在综合征患者中 (主要是NBCCS) 发现了76.9%.
结论:
- 患有NBCCS的患者表现出高于非综合征性OKC患者的OKC复发率.
- 在患有NBCCS的患者中,发展第二次原发性OKC的风险显著增加.
- 在这项研究中,没有确定OKC复发的统计学上显著的风险因素.
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