IVIM-Morph:以运动补偿的定量内声素不一致运动 (IVIM) 分析,用于从扩散权重的MRI数据中评估功能性胎儿肺成熟度
Noga Kertes1, Yael Zaffrani-Reznikov1, Onur Afacan2
1Faculty of Biomedical Engineering, Technion, Haifa, Israel.
ArXiv
|February 5, 2024
概括
一个新的深度学习模型,IVIM-morph,在扩散加权成像 (DWI) 中纠正胎儿运动,以准确评估肺成熟. 这种方法增强了成像生物标志物与妊娠年龄之间的相关性,为非侵入性胎儿发育监测铺平了道路.
科学领域:
- 医疗成像医学成像
- 生物物理学的生物物理.
- 机器学习 机器学习
背景情况:
- 扩散权重成像 (DWI) 显示出评估胎儿肺成熟的前景.
- 在MRI采集过程中胎儿运动显著阻碍了DWI数据的定量分析.
- 现有的运动校正方法往往无法保持定量DWI分析的完整性.
研究的目的:
- 引入IVIM-morph,一个自我监督的深度神经网络,用于对胎儿肺部DWI数据进行运动校正的定量分析.
- 为了能够同时估计声内不连贯运动 (IVIM) 模型参数和胎儿运动.
- 开发一种可靠的方法,用于生成胎儿肺成熟度的可靠成像生物标志物.
主要方法:
- 开发了IVIM-morph,这是一个具有集成注册和IVIM模型合适子网络的深度神经网络.
- 引入了生物物理知情损失函数,以平衡图像注册和IVIM模型拟合.
- 使用39名受试者的胎儿DWI数据验证了该模型,与六种基线方法进行了比较.
主要成果:
- 与所有基线方法相比,IVIM-morph证明了预测的IVIM参数和妊娠年龄 (GA) 之间的相关性明显改善.
- 在胎儿肺状阶段,在试验组中获得更高的相关系数 (例如0.44和0.52).
- 超越性能的方法包括无补偿,亲缘/可变形注册和其他深度学习方法.
结论:
- 对于定量DWI分析,IVIM-morph有效地纠正胎儿运动,从而能够准确评估胎儿肺部成熟度.
- 该模型显示了开发用于胎儿发育的非侵入性生物标志物的潜力.
- IVIM-morph的适应性表明在各种临床环境中对运动敏感的定量DWI分析中具有更广泛的应用.
相关概念视频
01:17Assessment of Diffusion and Perfusion
2.0K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
2.0K
01:24Magnetic Resonance Imaging
7.6K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
7.6K
01:21Imaging Studies for Cardiovascular System IV: CMRI
541
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
541
01:27Imaging Studies IV: Magnetic Resonance Imaging
427
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
427