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Updated: Jul 4, 2025

Induction and Validation of Cellular Senescence in Primary Human Cells
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Induction and Validation of Cellular Senescence in Primary Human Cells

Published on: June 20, 2018

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衰老期间的中粒体不活化可以在人类细胞中得到挽救

Sweta Sikder, Songjoon Baek, Truman McNeil

    bioRxiv : the preprint server for biology
    |February 5, 2024
    PubMed
    概括

    由于表观遗传变化,衰老的人类细胞显示中心蛋白CENP-A的减少. 双重抑制p53和LSD1/KDM1A重新激活细胞中体,使细胞复原.

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