50岁或以上的住院患者的肠道准备方案:一个随机对照试验
Yu He1, Qi Liu2, Yi-Wen Chen1
1Department of Geriatrics, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
World journal of gastrointestinal endoscopy
|February 5, 2024
概括
使用2-L聚乙烯糖醇 (PEG) 与乳糖和低残留饮食的新肠道制备方案与标准的4-L PEG对于结肠镜一样有效. 这种改进的治疗方案为老年人提供了更大的患者舒适性和更好的睡眠质量.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
背景情况:
- 结肠直肠癌的发病率和死亡率随着年龄的增长而增加,特别是在50岁以后.
- 定期的结肠镜检查对于50岁及以上的人来说至关重要.
- 患者对标准的4升聚乙烯糖醇 (PEG) 肠道制剂的耐受性较差,阻碍了定期的结肠镜检查.
研究的目的:
- 评估一个有效和舒适的肠道准备方案,用于住院的50岁及以上的患者.
- 为了比较一种新的饮食方案 (2L PEG + 乳糖 + 低残留饮食) 与标准的4L PEG制剂.
主要方法:
- 随机对照试验比较2-L PEG与乳糖和低残留饮食 (第一组) 与4-L PEG (第二组).
- 通过使用波士顿肠道准备量表 (BBPS) 评价的充足的肠道准备值≥6.
- 通过问卷评估患者的舒适度,包括睡眠时间和觉醒.
主要成果:
- 2L PEG疗法在治疗意图和每条协议分析中 (91.2%对91.0%) 与4L PEG相比,实现了非劣质的疗效 (BBPS ≥6).
- 在75岁及以上的患者中,疗效保持不变 (90.9% vs 97.0%).
- 第一组报告的舒适度得分明显高,睡眠时间较长,醒来次数较少于第二组.
结论:
- 2L PEG,乳糖和低残留饮食的肠道准备方案与50岁及以上的住院患者的4L PEG方案同样有效.
- 这种替代疗法显著提高了患者的舒适度,睡眠质量和整体耐受性.
- 这种优化方案解决了老年人定期进行结肠镜查的关键障碍.
相关概念视频
Lower GI Series: Barium Enema
279
A Barium Enema, or a lower GI series, is a specialized radiographic examination designed to visualize the lower gastrointestinal tract, specifically the colon and rectum. This procedure is instrumental in diagnosing various conditions such as colorectal cancer, polyps, diverticulosis, and inflammatory bowel disease.
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
279
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
88
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
88
Endoscopic Procedures II: Colonoscopy
99
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
99
Upper GI Series: Barium Swallow
341
The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues.
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...
341
Drugs for Treatment of Diarrhea-Predominant IBS
175
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
175
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
334
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
334


