奎瑞口水的配方和对关键病原体的抗微生物潜力:体外评估
Akshayaa L1, Jishnu Krishna Kumar2, Rajeshkumar Shanmugam3
1Public Health Dentistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus
|February 5, 2024
概括
奎尔丁口水表现出对口腔病原体具有显著的抗菌活性,优于商业草药口水. 这种天然的黄胺显示出作为口腔卫生和斑块控制的有效药物具有前途.
科学领域:
- 口腔微生物学 口腔微生物学
- 自然产品化学 自然产品化学
- 药理学 药理学是指药理学的学科.
背景情况:
- 草药口水使用植物疗法植物精油,其活性化合物包括儿茶素和色素.
- 奎尔是一种普遍存在的天然黄类化合物,表现出多种生物活性,包括抗氧化,抗炎和抗菌性质.
- 之前的研究表明奎尔素的抗菌疗效和生物相容性,表明其在口腔护理中的潜力.
研究的目的:
- 制定和评估一种含有瑞的新型口水的抗菌有效性.
- 为了比较奎尔丁口水与商业上可用的草药口水 (喜马拉雅Hiora) 的疗效.
主要方法:
- 通过添加quercetin, Lauryl 硫酸盐,甲基和糖糖来制备一个奎尔西口水.
- 使用阿加尔-井扩散方法对五种口腔病原体进行了抗菌活性评估.
- 奎尔塞丁口水与喜马拉雅Hiora口水作为对照进行了比较.
主要成果:
- 奎尔丁口水表现出显著的抗菌活性,在100μL度下,可见的抑制区域对*金黄色葡萄球菌*具有显著的抑制作用.
- 增加奎尔丁度导致口腔病原体抑制区域显著增加.
- 与商业草药口水相比,奎尔素配方显示出更好的抗菌作用.
结论:
- 奎尔丁口水具有相当大的抗菌性质,优于标准的草药口水.
- 这些发现表明,奎尔塞丁口水的潜力可以作为化学斑块控制的辅助疗法.
- 需要进行进一步的临床研究,以确定奎尔素口水作为口腔健康的常规或治疗性抗菌剂.
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