基于-复合物的食补充剂,促进长寿和健康的生活
Andrei Biţă1,2, Ion Romulus Scorei1, Tudor Adrian Bălşeanu1,3
1Department of Biochemistry, BioBoron Research Institute, S.C. Natural Research S.R.L., Podari, Dolj County, Romania.
Current health sciences journal
|February 5, 2024
概括
-复合物 (ZBC) 食补充剂是稳定的,无毒的,并被很好地吸收,通过增加α2-巨型球蛋白 (A2M) 表达来促进长寿. ZBC被快速代谢和分泌,在慢性研究中观察到A2M水平的峰值.
科学领域:
- 营养科学 营养科学
- 生物化学 生物化学
- 毒理学 毒理学 毒理学
背景情况:
- (Zn) 和 (B) 在植物-动物-人类营养途径中起着至关重要的作用.
- 研究用于提供必需矿物质的新型配方是全球研究的优先事项.
研究的目的:
- 为了评估-复合物 (ZBC) 食补充剂的营养和生理影响.
- 评估ZBC的安全性,吸收,新陈代谢和分泌特征.
- 为了确定ZBC对alpha2-macroglobulin (A2M) 表达的影响,以获得潜在的健康益处.
主要方法:
- 基于-复合物 (ZBC) 的食补充剂的开发和表征.
- 在急性,次慢性和慢性实验环境中给小鼠注射ZBC.
- 通过免疫吸收性测定评估肠道吸收,新陈代谢,尿液分泌和肝脏A2M蛋白水平.
主要成果:
- ZBC配方表现出稳定性,无毒性和高肠道吸收率.
- 通过水解,ZBC被快速代谢,并在7小时内主要通过尿液排出.
- 观察到肝脏A2M蛋白的显著诱导,在慢性实验中达到最高水平 (1000mg/kg).
结论:
- -复合物 (ZBC) 是一个有前途的,生物可用和安全的食补充剂.
- 施用ZBC有效诱导alpha2-macroglobulin (A2M) 表达,这表明它有可能促进长寿和健康的衰老.
- ZBC的快速新陈代谢和分泌特征支持其在口服补充剂中的安全性.
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