在患有急性淋巴细胞白血病的患者中,四分位CAR-T细胞桥接到两次Allo-HSCT疗法
Qing Zhang1, Yi Dong1, Zhimin Zhai1
1Department of Hematology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
概括
重复的CAR-T细胞疗法和allo-HSCT可以成为复发性或耐药性急性淋巴细胞白血病 (ALL) 患者的安全和有效策略. 当其他疗法失败时,这种方法提供了一个可行的治疗选择.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 血液学 血液学 血液学
背景情况:
- 化学抗原受体T (CAR-T) 细胞疗法和全源造血干细胞移植 (allo-HSCT) 是针对复发性或耐药性急性淋巴细胞白血病 (ALL) 的已确立治疗方法.
- 由于患者特异性因素,获得重复性CAR-T细胞疗法和allo-HSCT的挑战限制了一些人的治疗选择.
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