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相关概念视频

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

67
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
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Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring
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在肝移植中实施出血管理算法:试点研究

Ignacio A Sarmiento1, María F Guzmán2, Javier Chapochnick3

  • 1Department of Anesthesiology, Clínica Santa María, Santiago de Chile, Chile.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie
|February 5, 2024
PubMed
概括

一个新的出血管理算法显著减少了肝移植患者的血液产品使用. 该研究还证实了对这一关键手术程序进行更大规模的多中心随机试验的可行性.

关键词:
流血 出血 流血 出血血液静止 血液静止 血液静止肝脏移植是什么?肝移植是什么?粘弹性测试 粘弹性测试

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科学领域:

  • 移植手术 移植手术
  • 肝病学 肝病学是一种肝病学.
  • 麻醉学和重症监护医学

背景情况:

  • 肝移植是末期肝病的救生手术.
  • 高手术出血风险是肝移植患者的主要并发症.
  • 有效的出血管理对于患者的治疗结果至关重要.

研究的目的:

  • 在肝移植接受者实施出血管理算法之前和之后,比较血液产品的消耗.
  • 为了评估一个多中心的可行性,对这个算法进行随机研究.
  • 评估算法对输血要求和患者结果的影响.

主要方法:

  • 对30名肝移植患者的回顾性分析,分为两组:算法实施前和后.
  • 该算法集成了粘弹性测试和冷解凝固因子缩物 (前热复合物和纤维素缩物).
  • 主要结局:手术后24小时输血产品输血量. 二次结果:住院,死亡率和成本.

主要成果:

  • 算法组 (组2) 与算法前组 (组1) (33个单位) (p=0.028) 相比,平均24小时血液产品消费量 (1.5个单位) 显著减少.
  • 红细胞,新鲜冷血和冷沉积物的输血在算法组明显较低.
  • 两组之间并发症,住院或死亡率没有显著差异.

结论:

  • 实施的静血管理算法在肝移植后24小时内显著降低了血液产品的利用率.
  • 该研究成功证明了这种方法的可行性,并为未来的随机试验提供了样本大小计算的数据.
  • 这种算法代表了优化肝移植手术中的血液管理的有希望的策略.