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Updated: Jul 4, 2025

Quantifying Antibody-Dependent Cellular Cytotoxicity in a Tumor Spheroid Model: Application for Drug Discovery
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通过抑制COUP-TFII,阿斯特拉加索酸IV减轻了与苏尼替尼相关的心脏毒性

Wanting Qin1, Shaoling Li2, Ziji Cheng1

  • 1Department of Anatomy, College of Chinese Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.

Heliyon
|February 5, 2024
PubMed
概括

甲酸IV (ASIV) 通过减少炎症,氧化应激和亡,保护免受苏尼替尼 (SU) 诱导的心脏损伤. 通过抑制COUP-TFII表达,ASIV可以改善SU的心脏毒性.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.阿斯特拉加洛西德IV在COUP-TFIIII中,我们可以氧化应激是一种氧化应激.与苏尼提尼布相关的心脏毒性

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